THERAPEUTIC INDICATIONS
It is particularly suitable for the treatment of diseases where a powerful and effective antibacterial action is required against microorganisms sensitive to the sulfamethoxazole-trimethoprim association (gram-positive, gram-negative), in particular: escherichia, streptococcus, proteus, salmonella, pasteurella, shigella, haemophilus, staphilococcus, neisseria, klebsiella, fusiformis, corynebacterium, clostridium, bordetella. Noxaprim® is therefore indicated for the therapeutic treatment of: respiratory infections, such as equine adenitis, abscesses of guttural pockets, laryngitis, tracheitis, acute and chronic bronchitis, bronchopneumonia, pneumonia, pleurisy, pleuropneumonia etc .; urogenital infections, such as cystitis, urethritis, pyelitis, nephritis, metritis, vaginitis, orchitis, balanoposthitis, etc .; gastrointestinal infections, such as gastritis, enteritis, colitis, in the course of resolution of colic syndromes or in the medium and long-term postoperative course of gastrointestinal tract surgery; - infections of the skin of the soft tissues: pyoderma, abscesses, accidental or surgical wounds, burns etc .; skeletal infections: septic arthritis and arthrosynovitis, bacterial diseases of the foot ("road nail wounds"), osteomyelitis etc.
DOSAGE AND METHOD OF ADMINISTRATION
Adult horses: the recommended dose is 10 g of noxaprim® / 100 kg of weight, equal to 3.33 g of sulfamethoxazole / 100 kg / bw. and 0.67 g of trimetropin / 100 kg / bw, as an attack dose (40-80 cc per day) on the first day and 5 g / 100 kg of weight as a maintenance dose (20-40 cc per day) in following days.
Foals and ponies: the recommended dose is 10 g of noxaprim® / 100 kg of weight as a starting dose (20-40 cc per day) on the first day and 5 g / 100 kg of weight as a maintenance dose (10- 20 cc per day) in the following days.
It is recommended to reach the desired daily dose by administering noxaprim® every 12 hours. The duration of treatment is usually 5-7 days, it is advisable to continue therapy for at least 2-3 days after the complete disappearance of clinical symptoms. If no benefit is seen in acute conditions after 3-5 days, re-evaluate the diagnosis. To avoid over-underdosing, body weight should be determined as accurately as possible. In order to obtain the correct dosage, the concentration of the antibiotic must be calculated accordingly.
